Do you really think that it is because Rh Antibody are more immunologic than ABO ones? Ofcourse not! Just think about a patient that has received a non-matched blood transfusion, and see how dangerous that could be. So ABO Antibodies are even more immunologic than Rh ones.
The reason is that Antibodies to ABO antigens belong to IgM antibody class so they do not cross placenta and hence mother and baby can have different blood type. But Anti-D antibodies (the major part of Rh Antibodies) that are responsible for Rh alloimmunization belong to IgG class and do cross placenta.
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment