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Sunday, September 16, 2007

Absence Seizure

Presentation: child is referred to you by teacher telling that he has problem with dictation and has multiple word loss during writing, or mom tells you the child has several spell out that he is not aware of the around situation and comes back to normal situation abruptly.

Classic EEG: symetric 3mhtz spike and wave.

Treatment: Ethosuximide is treatment of choice. Second line is Valproate

Attention: Phenytoin and Carbamazapine are first line drug used for primary generalized tonic clonic sezure or partial seizures, both work by blocking Na channels voltage dependent, Phenytoin is a second drug line for myoclonic and tonic clonic seizure, its available in both IV and oral forms, side effects are gingivial hypertrophy, lymphadenopathy, hirsutism and rash, Both Phenytoina & Carbamazepine can cause Steven Johnson syndrome and Toxic Epidermal Necrolysis (TEN).

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